LymphedemaV1, Main, Exploration, bibRecord, 001617

Weight Lifting and Physical Function Among Survivors of Breast Cancer: A Post Hoc Analysis of a Randomized Controlled Trial

Identifieur interne : 001617 ( Main/Exploration ); précédent : 001616; suivant : 001618

Weight Lifting and Physical Function Among Survivors of Breast Cancer: A Post Hoc Analysis of a Randomized Controlled Trial

Auteurs : Justin C. Brown ; Kathryn H. Schmitz

Source :

Journal of Clinical Oncology [ 0732-183X ] ; 2015.

RBID : PMC:4477788

Descripteurs français

KwdFr :
- Adulte d'âge moyen, Aptitude physique, Femelle, Haltérophilie, Humains, Lymphoedème (), Lymphoedème (étiologie), Méthode en simple aveugle, Survivants, Tumeurs du sein ().
MESH :
- étiologie : Lymphoedème.
- Adulte d'âge moyen, Aptitude physique, Femelle, Haltérophilie, Humains, Lymphoedème, Méthode en simple aveugle, Survivants, Tumeurs du sein.

English descriptors

KwdEn :
- Breast Neoplasms (complications), Female, Humans, Lymphedema (etiology), Lymphedema (prevention & control), Middle Aged, Physical Fitness, Single-Blind Method, Survivors, Weight Lifting.
MESH :
- complications : Breast Neoplasms.
- etiology : Lymphedema.
- prevention & control : Lymphedema.
- Female, Humans, Middle Aged, Physical Fitness, Single-Blind Method, Survivors, Weight Lifting.

Abstract

Purpose

Survivors of breast cancer may experience deterioration of physical function. This is important because poor physical function may be associated with premature mortality, injurious falls, bone fracture, and disability. We conducted a post hoc analysis to explore the potential efficacy of slowly progressive weight lifting to reduce the incidence of physical function deterioration among survivors of breast cancer.

Methods

Between October 2005 and August 2008, we conducted a single-blind, 12-month, randomized controlled trial of twice-per-week slowly progressive weight lifting or standard care among 295 survivors of nonmetastatic breast cancer. In this post hoc analysis of data from the Physical Activity and Lymphedema Trial, we examined incident deterioration of physical function after 12 months, defined as a ≥ 10-point decrease in the physical function subscale of the Medical Outcomes Short-Form 36-item questionnaire.

Results

The proportion of participants who experienced incident physical function deterioration after 12 months was 16.3% (24/147) in the control group and 8.1% (12/148) in the weight lifting group (relative risk, 0.49; 95% CI, 0.25 to 0.96; P = .04). No serious or unexpected adverse events occurred that were related to weight lifting.

Conclusion

Slowly progressive weight lifting compared with standard care reduced the incidence of physical function deterioration among survivors of breast cancer. These data are hypothesis generating. Future studies should directly compare the efficacy of weight lifting with other modalities of exercise, such as brisk walking, to appropriately inform the development of a confirmatory study designed to preserve physical function among survivors of breast cancer.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477788

DOI: 10.1200/JCO.2014.57.7395
PubMed: 25964257
PubMed Central: 4477788

Affiliations:

Le document en format XML

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<term>Humains</term>
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<front><div type="abstract" xml:lang="en"><sec><title>Purpose</title>
<p>Survivors of breast cancer may experience deterioration of physical function. This is important because poor physical function may be associated with premature mortality, injurious falls, bone fracture, and disability. We conducted a post hoc analysis to explore the potential efficacy of slowly progressive weight lifting to reduce the incidence of physical function deterioration among survivors of breast cancer.</p>
</sec>
<sec><title>Methods</title>
<p>Between October 2005 and August 2008, we conducted a single-blind, 12-month, randomized controlled trial of twice-per-week slowly progressive weight lifting or standard care among 295 survivors of nonmetastatic breast cancer. In this post hoc analysis of data from the Physical Activity and Lymphedema Trial, we examined incident deterioration of physical function after 12 months, defined as a ≥ 10-point decrease in the physical function subscale of the Medical Outcomes Short-Form 36-item questionnaire.</p>
</sec>
<sec><title>Results</title>
<p>The proportion of participants who experienced incident physical function deterioration after 12 months was 16.3% (24/147) in the control group and 8.1% (12/148) in the weight lifting group (relative risk, 0.49; 95% CI, 0.25 to 0.96; <italic>P</italic>
 = .04). No serious or unexpected adverse events occurred that were related to weight lifting.</p>
</sec>
<sec><title>Conclusion</title>
<p>Slowly progressive weight lifting compared with standard care reduced the incidence of physical function deterioration among survivors of breast cancer. These data are hypothesis generating. Future studies should directly compare the efficacy of weight lifting with other modalities of exercise, such as brisk walking, to appropriately inform the development of a confirmatory study designed to preserve physical function among survivors of breast cancer.</p>
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Weight Lifting and Physical Function Among Survivors of Breast Cancer: A Post Hoc Analysis of a Randomized Controlled Trial

Weight Lifting and Physical Function Among Survivors of Breast Cancer: A Post Hoc Analysis of a Randomized Controlled Trial

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le lymphœdème
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